Fibronectinisahigh-molecularweightglycoproteinoftheextracellularmatrix.Itisofmajorimportanceforcelladhesion,growth,migration,anddifferentiation.Fibronectinbindstoextracellularmatrixcomponents,suchascollagen,heparinsulfateproteoglycansorcollagen.Fur
Thermore,aspartofthefamilyofextracellularmatrixproteins(ECM)itfacilitatesthedeliveryofgrowthfactorstocells.Fibronectinhasprofoundeffectsonwoundhealing,includingtheformationofpropersubstratumformigrationandgrowthofcellsduringthedevelopmentandorganizationofgranulationtissue,aswellasremodelingandresynthesisoftheconnectivetissuematrix.ThehumanFibronectin(Fragment)isarecombinantengineeredproteinfragmentcomposedoftwofunctionaldomainsofthefulllengthprotein.