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Abnova/ABCB1 recombinant monoclonal antibody, clone MRK16/1kit/RAB00101
  • Abnova/ABCB1 recombinant monoclonal antibody, clone MRK16/1kit/RAB00101

Abnova/ABCB1 recombinant monoclonal antibody, clone MRK16/1kit/RAB00101

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货号: RAB00101
品牌: Abnova
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  • 详情
  • 使用说明
  • 常见问题
      • Specification
      • Product Description:
      • Recombinant rabbit monoclonal antibody raised against human ABCB1.
      • Immunogen:
      • Original antibody is raised against drug resistant K-562 cells.
      • Reactivity:
      • Human
      • Specificity:
      • This antibody recognizes a discontinuous extracellular epitope on ABCB1.
      • Form:
      • Liquid
      • Purification:
      • Protein A affinity purification
      • Isotype:
      • IgG, kappa
      • Recommend Usage:
      • Flow Cytometry (1 ug/mL)ImmunofluorescenceImmunoprecipitation (10 ug/mL)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS, pH 7.2 (0.02% Proclin 300).
      • Storage Instruction:
      • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Antibody Species:
      • Rabbit
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Immunofluorescence
      • Immunoprecipitation
      • Flow Cytometry
      • Application Image
      • Immunofluorescence
      • Immunoprecipitation
      • Flow Cytometry
      • Gene Information
      • Entrez GeneID:
      • 5243
      • Protein Accession#:
      • P08183
      • Gene Name:
      • ABCB1
      • Gene Alias:
      • ABC20,CD243,CLCS,GP170,MDR1,MGC163296,P-GP,PGY1
      • Gene Description:
      • ATP-binding cassette, sub-family B (MDR/TAP), member 1
      • Omim ID:
      • 171050
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq
      • Other Designations:
      • ATP-binding cassette, subfamily B, member 1,P glycoprotein 1,P-glycoprotein 1,colchicin sensitivity,doxorubicin resistance,multidrug resistance 1,multidrug resistance protein 1
      • Gene Pathway
      • ABC transporters
      • Related Disease
      • Acquired Immunodeficiency Syndrome
      • Acute Disease
      • Addison Disease
      • Adenocarcinoma
      • Adenoma
      • Alcoholism
      • Alzheimer Disease
      • Alzheimer disease
      • Amnesia
      • Anemia
      • Arthritis, Rheumatoid
      • Asthma
      • Asthma
      • Atherosclerosis
      • Attention Deficit Disorder with Hyperactivity
      • Bipolar Disorder
      • Birth Weight
      • Body Weight
      • Brain Neoplasms
        • ... see more
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