Tocris/Fasentin/6100/10/10 mg188bio精品生物—专注于实验室精品爆款的电商平台

BiologicalActivity

GLUT1andGLUT4inhibitor(IC₅₀=68μM).PreferentiallyinhibitsGLUT4overGLUT1.SensitizesFasreceptorinarangeoftumorcelllines(IC₅₀=20μM)bymodulatingtheextrinsicapoptoticpathwaydownstreamofTNFreceptorsbutupstreamofeffectorcaspases.

TechnicalData

M.Wt	279.64
Formula	C₁₁H₉ClF₃NO₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	392721-37-8
PubChemID	879520
InChIKey	GNYIJZMBLZXJEJ-UHFFFAOYSA-N
Smiles	CC(CC(NC1=CC(C(F)(F)F)=C(C=C1)Cl)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.96	100
	ethanol	27.96	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight279.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.58mL	17.88mL	35.76mL
5mM	0.72mL	3.58mL	7.15mL
10mM	0.36mL	1.79mL	3.58mL
50mM	0.07mL	0.36mL	0.72mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.