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Tocris/KHS 101 hydrochloride/4888/10/10 mg
  • Tocris/KHS 101 hydrochloride/4888/10/10 mg

Tocris/KHS 101 hydrochloride/4888/10/10 mg

价格: ¥1860.00 市场价: 3100.00

货号: 4888/10
品牌: Tocris
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    • Description:SelectiveinducerofneuronaldifferentiationinhippocampalneuralProgenitors
      ChemicalName:N4-(2-Methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediaminehydrochloride
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Selectiveinducerofneuronaldifferentiation;inducesneuronaldifferentiationinculturedhippocampalneuralprogenitorcells(NPCs)byinteractingwithTACC3(EC50~1μM).Suppressesastrocyteformation.Alsoinducesaccelerationofneuronaldifferentiationinthehippocampaldentategyrusinvivo.

      CompoundLibraries

      KHS101hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt375.92
      FormulaC18H21N5S.HCl
      StorageDesiccateatRT
      Purity≥98%(HPLC)
      PubChemID90488983
      InChIKeyINVQHPQJFRKGIO-UHFFFAOYSA-N
      SmilesCC(C)CNC1=NC(NCC2=CSC(C3=CC=CC=C3)=N2)=NC=C1.Cl

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO18.850
      ethanol18.850

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight375.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.66mL13.3mL26.6mL
      5mM0.53mL2.66mL5.32mL
      10mM0.27mL1.33mL2.66mL
      50mM0.05mL0.27mL0.53mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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