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Tocris/Purmorphamine/4551/10/10 mg
  • Tocris/Purmorphamine/4551/10/10 mg

Tocris/Purmorphamine/4551/10/10 mg

价格: ¥2268.00 市场价: 3780.00

货号: 4551/10
品牌: Tocris
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    • Description:SmoreceptoragoNIST
      ChemicalName:9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Smoothened(Smo)receptoragonist(EC50~1μM).InducesosteogenesisinmousemesenchymalProgenitorcells(C3H10T1/2).WhencombinedwithBMP-4,cantransdifferentiatepre-ADIpocytes(3T3-L1)andmyoblasts(C2C12)intoosteoblasts.Inducesdifferentiationofmultipotentmesenchymalprogenitorcellsintoosteoblasts.

      CompoundLibraries

      PurmorphamineisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt520.62
      FormulaC31H32N6O2
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      CASNumber483367-10-8
      PubChemID5284329
      InChIKeyFYBHCRQFSFYWPY-UHFFFAOYSA-N
      SmilesC1(OC4=CC=CC5=C4C=CC=C5)=NC(NC3=CC=C(N6CCOCC6)C=C3)=C2C(N(C7CCCCC7)C=N2)=N1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO52.06100

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight520.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.92mL9.6mL19.21mL
      5mM0.38mL1.92mL3.84mL
      10mM0.19mL0.96mL1.92mL
      50mM0.04mL0.19mL0.38mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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