Biological Activity
Technical Data
Solubility
Calculators
Datasheets
References
Biological Activity
Endocytosis inhibitor that blocks the interaction of dynamin with amphiphysin 1 and 2. Impairs AMPA receptor cycling and blocks DHPG-induced long term depression (LTD).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solubility
Soluble to 1 mg/ml in water
Preparing Stock Solutions
The following data is based on the product molecular weight 1566.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
1 mM
0.64 mL
3.19 mL
6.38 mL
5 mM
0.13 mL
0.64 mL
1.28 mL
10 mM
0.06 mL
0.32 mL
0.64 mL
50 mM
0.01 mL
0.06 mL
0.13 mL
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets
Certificate of Analysis / Product Datasheet
Safety Datasheet
Select another language:
View SDS
References
References are publications that support the products' biological activity.
Lüscheret al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649 PMID: 10595516
Xiaoet al (2001) Metabolic glutamate receptor activation causes a rapid redistribution of AMPA receptors. Neuropharmacology 41 664 PMID: 11640920
Wigge and McMahon
(1998) The amphiphysin family of proteins and their role in endocytosis at the synapse. Trends Neursci. 21 339 PMID: