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Tocris/Bax channel blocker/2160/10/10 mg
  • Tocris/Bax channel blocker/2160/10/10 mg

Tocris/Bax channel blocker/2160/10/10 mg

价格: ¥2100.00 市场价: 3500.00

货号: 2160/10
品牌: Tocris
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    • Description:InhibitsBax-mediatedmitochondrialcytochromecrelease
      ChemicalName:3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanoldihydrochloride
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      PotentinhibitorofBax-mediatedmitochondrialcytochromecrelease(IC50=0.52μM).SuggestedtoinhibitBaxchannelformation/activity.

      CompoundLibraries

      BaxchannelblockerisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt540.12
      FormulaC19H21Br2N3O.2HCl
      StorageDesiccateatRT
      Purity≥98%(HPLC)
      CASNumber329349-20-4
      PubChemID2729026
      InChIKeyHWFKCAFKXZFOQT-UHFFFAOYSA-N
      SmilesCl.Cl.OC(CN1C2=C(C=C(Br)C=C2)C2=C1C=CC(Br)=C2)CN1CCNCC1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO46.72100
      water2.345

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight540.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.85mL9.26mL18.51mL
      5mM0.37mL1.85mL3.7mL
      10mM0.19mL0.93mL1.85mL
      50mM0.04mL0.19mL0.37mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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