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Tocris/Taxol/1097/10/10 mg
  • Tocris/Taxol/1097/10/10 mg

Tocris/Taxol/1097/10/10 mg

价格: ¥1548.00 市场价: 2580.00

货号: 1097/10
品牌: Tocris
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    • Description:Promotesassemblyandinhibitsdisassemblyofmicrotubules
      AlternativeNames:Paclitaxel
      ChemicalName:[2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylesterbenzenepropanoicacid
      Purity:≥99%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      Antitumoragent;promotesandstABIlizestubulinpolymerization,causingcellcyclearrest.Inducesautocatalyticactivationofcaspase-10inCCRF-HSB-2cells,triggeringapoptosis.

      CompoundLibraries

      TaxolisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

      TechnicalData

      M.Wt853.92
      FormulaC47H51NO14
      StorageStoreat+4°C
      Purity≥99%(HPLC)
      CASNumber33069-62-4
      PubChemID441276
      InChIKeyRCINICONZNJXQF-VAZQATRQSA-N
      SmilesO=C2[C@@]3(C)C([C@@]4(OC(C)=O)[C@H](OC4)C[C@@H]3O)[C@H](OC(C7=CC=CC=C7)=O)[C@@]1(O)[C@](C)(C)C([C@H]2OC(C)=O)=C(C)[C@@H](OC([C@H](O)[C@H]([C@]5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C1

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO85.39100mMwithgentlewarming
      ethanol21.3525

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight853.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM1.17mL5.86mL11.71mL
      5mM0.23mL1.17mL2.34mL
      10mM0.12mL0.59mL1.17mL
      50mM0.02mL0.12mL0.23mL

      ProductDatasheets

      CertificateofAnalysis/ProductDatasheet
      SafetyDatasheet

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