Regulatorystatus:Forresearchuseandexvivocellprocessingonly
AvailABIlity:worldwide(1)
Content:500mLOverview
iPS-BrewGMPMediumisaxeno-andserum-freemediumformulationthathasbeendevelopedforthemaintenanceofundifferentiatedpluripotentstemcellsunderfeeder-freeconditions.Thecompletemediumiscomposedofthespecificallyformulated“iPS-BrewGMPBasalMedium”aswellastheoptimized“iPS-BrewGMPSupplementR”thatwhenusedtogethersupportlong-termgrowthandmaintenanceofundifferentiatedcells.
RecombinanthumanTGF-β1hastobeaddedtothecompletemediumforthemaintenanceandexpansionofhumanpluripotentstemcells.
Disclaimer
MACSGMPProductsareforresearchuseand
exvivocellcultureprocessingonly,andarenotintendedforhuman
invivoapplications.ForregulatorystatusintheUSA,pleasecontactyourlocalrepresentative.
Details
Backgroundinformation
iPS-BrewGMPMediumisbasedontheformulationofStemMACSiPS-BrewXF(#130-104-368)thusenablingseamlesstranslationfromresearchtoclinicalapplications.
- Serum-freeandxeno-freeformulation
- Manufacturedunderstrictlycontrolledconditions
- Consistentlot-to-lotperformance
- Qualitycontrol:functionalitytestoneverybatch
- 500mLbottles–withoutphenolred
- RecombinanthumanTGF-ß1hastobeaddedtothemedium
Applications
iPS-BrewGMPMediumhasbeendevelopedforthemaintenanceandexpansionofhumanpluripotentstemcellsonstandardcellattachmentmatrices,e.g.Laminin521.
Qualitystatement
MACSGMPProductsaremanufacturedandtestedunderaqualitymanagementsystem(ISO13485)andareincompliancewithrelevantGMPguidelines.Theyaredesignedfollowingtherecommendationsof
USP<1043>onancillarymaterials.