TheBloodDendriticCellEnumerationKitwasdevelopedforeasyidentificationandenumerationofdendriticcells(DCs)andDCsubsetsinwholebloodorPBMCsbyflowcytometry.Allreagentsrequiredfortheanalysisareincludedinthekit.
ApplicationsofthekitincludemonitoringofperipheralbloodDCfrequencyandnumber,forexample,afterhematopoieticstemcellmobilization
3,orinthecourseofpathogenicinfections,forexamplebyHIV.
4Fur
Thermore,DCnumbersweredeterminedinpatientswithchronicgraftversushostdisease
5,inflammatoryboweldisease
6,psoriaticarthritisandrheumatoidarthritis
10,underlong-termimmunosuppression
8,lymphoproliferativediseaseofgranularlymphocytes
9,orinpatientswithhepatocellularcarcinoma,inordertoanalyzetheimmunosuppressiveroleofIL-10oncirculatingdendriticcells
7.